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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SERPINA1 All Species: 19.39
Human Site: Y321 Identified Species: 60.95
UniProt: P01009 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P01009 NP_000286.3 418 46737 Y321 K L S I T G T Y D L K S V L G
Chimpanzee Pan troglodytes P61640 415 46307 Y314 K F S I S A T Y D L G A T L L
Rhesus Macaque Macaca mulatta XP_001099150 418 46681 Y321 R L A I T G T Y D L K T V L G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P22599 413 45956 Y315 R L S I S G D Y N L K T L M S
Rat Rattus norvegicus P17475 411 46117 Y315 K L S I S G T Y N L K T L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518875 498 56680 I326 K F S I S G Q I K L E K I L P
Chicken Gallus gallus XP_421344 437 49694 Y339 K V S I S G T Y D L K K M A M
Frog Xenopus laevis NP_001081358 433 48891 L337 K F S I S A E L D L I E V F K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.1 91.6 N.A. N.A. 64.3 68.6 N.A. 39.1 45.3 48.2 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 61.2 96.8 N.A. N.A. 81.5 84.2 N.A. 54.8 65.2 64.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 53.3 80 N.A. N.A. 46.6 66.6 N.A. 40 60 40 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 N.A. N.A. 86.6 93.3 N.A. 60 80 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 25 0 0 0 0 0 13 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 13 0 63 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 13 0 0 0 13 13 0 0 0 % E
% Phe: 0 38 0 0 0 0 0 0 0 0 0 0 0 13 0 % F
% Gly: 0 0 0 0 0 75 0 0 0 0 13 0 0 0 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 100 0 0 0 13 0 0 13 0 13 0 0 % I
% Lys: 75 0 0 0 0 0 0 0 13 0 63 25 0 0 13 % K
% Leu: 0 50 0 0 0 0 0 13 0 100 0 0 25 63 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 13 13 13 % M
% Asn: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % P
% Gln: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 88 0 75 0 0 0 0 0 0 13 0 0 25 % S
% Thr: 0 0 0 0 25 0 63 0 0 0 0 38 13 0 0 % T
% Val: 0 13 0 0 0 0 0 0 0 0 0 0 38 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _